Research Projects

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InoCardia: Human Traberculae Work-Loop Feasibility

The aim of this project was to develop a test that uses human heart muscle tissue in a way that can efficiently test many drugs, to reduce the risk of any approved drugs causing damage to the heart.

Fundamental Movement Skills, Physical Activity and Obesity in British Children

This project aims to understand how early development of fundamental movement skills might impact on physical activity and body fatness in British children.

The Effectiveness of a Primary School Based Badminton Intervention on Children’s Fundamental Movement Skills

This project examined if a badminton based intervention is effective in enhancing fundamental movement skills, physical activity, motivation to undertake physical activity, fitness and health in children aged 7-9 years.

Coffee Ingestion: Interaction Between Sex and Cycling Performance

The aim of this study was to investigate whether sex differences exist with regard to 5 km cycling time trial performance and affective responses following the ingestion of 300 ml caffeinated coffee, a placebo (coffee flavoured solution) and a control (no fluid).

Commercialisation of a Micronutrient Delivery Platform for targeted iron absorption

The aim of this project is to commercialise our unique, newly developed, micronutrient delivery platform (MDP) for iron absorption, for safe, cost-effective and efficient iron delivery.

Review of Evidence on the Physiological and Psychological Development of Children

In 2015 the UK Government gave Sport England a new remit to support children aged 5-14 years. SE commissioned Duncan, Eyre and colleagues to undertake a review (completed in March 2017) to inform the body’s response to this.

Bioleaching technology for the recovery of metals from Electronic Waste - Research Project

The aim of the project is to develop a sustainable and environmentally friendly method to recover precious metals from electronic waste that will create a closed-loop system to recycle metals back into the supply chain as required in a sustainable circular economy.

Addressing GPCR conformational flexibility

The large G protein coupled receptor (GPCR) family is a highly interesting target for drug design because a large proportion of current drugs bind to its members, and because the family offers much potential to exploit new targets.

Identification of novel double-stranded RNA elements in developing antibiotic resistance in the agricultural environment

The goal of the project is to identify and subsequently characterise the dsRNA dimension of the animal gut microflora (both the differential presence of antisense bound to mRNA and phage dsRNAs containing novel genetic information in response to AB pressure). Identification of novel functional dsRNAs (asRNA bound to its target and phage dsRNAs involved in AR) will mark a paradigm shift in our understanding of the development of AR and future approaches to treating infections.

Investigating the function and substrate interaction network of ABHD16A, a novel regulator of protein S-acylation

This study aims to characterise the molecular mechanisms and functions of a novel APT, ABHD16A.

Comparison of RR intervals and heart rate variability between disposable and reusable electrocardiography leads

The aim of the project is to assess heart rate variability using novel disposable ECG leads in healthy subjects, and to assess the agreement between heart rate variability measures obtained using disposable and reusable electrocardiography leads.

InoCardia: Contractome-AI

Contractome-AI’s combination of novel assay and computational methods improves early detection of heart contractility issues, helping avoid expensive downstream problems.